Browsing by Subject "protein transport"
Now showing items 1-5 of 5
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Article
A Biophysical Model of Endocannabinoid-Mediated Short Term Depression in Hippocampal Inhibition
(2013)Memories are believed to be represented in the synaptic pathways of vastly interconnected networks of neurons. The plasticity of synapses, that is, their strengthening and weakening depending on neuronal activity, is ...
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Article
Calpain2 protease: A new member of the Wnt/Ca2+ pathway modulating convergent extension movements in Xenopus
(2013)Calpains are a family of calcium-dependent intracellular cysteine proteases that regulate several physiological processes by limited cleavage of different substrates. The role of Calpain2 in embryogenesis is not clear with ...
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Article
KIF1Bβ transports dendritically localized mRNPs in neurons and is recruited to synapses in an activity-dependent manner
(2013)KIF1Bβ is a kinesin-like, microtubule-based molecular motor protein involved in anterograde axonal vesicular transport in vertebrate and invertebrate neurons. Certain KIF1Bβ isoforms have been implicated in different forms ...
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Article
KIF2β, a new kinesin superfamily protein in non-neuronal cells, is associated with lysosomes and may be implicated in their centrifugal translocation
(1998)Lysosomes concentrate juxtanuclearly in the region around the microtubule-organizing center by interaction with microtubules. Different experimental and physiological conditions can induce these organelles to move to the ...
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Article
Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance
(2013)The purpose of this work is to determine the molecular mechanisms underlying tamoxifen resistance. We show here that ER-β is epigenetically silenced in a cell line with acquired tamoxifen resistance (MCF-7/TAM-R) and this ...